The FDA has warned of certain risks associated with the use of fluoroquinolones. In addition to possible tendinitis and tendon rupture, the FDA has cautioned that this class of drugs may also cause decreases in blood sugar levels and impact mental health.
Additionally, patients “with a history of blockages or aneurysms (abnormal bulges) of the aorta or other blood vessels, high blood pressure, certain genetic disorders that involve blood vessel changes, and the elderly” should avoid using fluoroquinolones unless there is no other treatment option available, as the use of fluoroquinolones in these patients can elevate the risk of aortic aneurysm. Though fluoroquinolones are associated with (and not a cause of) this adverse effect, patients and providers should be aware of this increased risk and manage prescribing accordingly.
Read more at MedPage Today or on the FDA website.