I went to NJH in Sept 2006. My ID doctor at Duke the suggested surgery. NJ didn’t. I guess the destruction is too far gone. Needless to say, I too am resistant to just about every drug that could possible help me. My doctor let me take a drug holiday from June of 2007 to January 2008 because of severe intestinal distress. I was taking high doses of meds everyday prescribed by NJ. I am now back on zithromax and ethambutol at a lower dose. I don’t know how much this is helping but it gives me some emotional security. Otherwise than that I just try to keep pushing forward with good eating habits, exercise, proper sleep and a positive outlook. These get me through each day.